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They live on our skin, in our hair, on our eyelashes, and in our gut

Low levels can cause a loss of balance, numbness or tingling in the arms and legs, weakness, fatigue, constipation, confusion, depression, poor memory, soreness of the mouth or tongue, weight loss, and a type of anemia known as megaloblastic anemia

Ca2+ provides favorable features as a secondary messenger and serves as one of the major components in the cellular signaling pathways of many organisms (Sanders et al., 1999)