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= 250 C

10.1038/ni1192 347

A low DAR might reduce efficacy, while a very high DAR can impair the antibodys structure or cause rapid clearance and toxicity

Uptake of MIM-dependent EVs at CIP4-localized sites To investigate the mechanism by which Rac1 in EVs exerts its effects in recipient cells, we visualized the localization of Rac1 within EVs during intracellular trafficking from endocytosis to endosomes (Fig