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We then treated the PPARa over-expression and knockdown cell lines with ferroptosis inducers to investigate whether PPARa exerts its anti-ferroptotic effects through the FSP1-CoQ10-NAD(P)H pathway

Constitutive and -naphthoflavone-induced expression of the human -glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence

10.1007/s10571-011-9755-5 22 BlakeA