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The specific goal at the start of these efforts was to create a short list of attractive Food and Drug Administration-approved drugs that could be tested rapidly in clinical trials without requiring a drug development effort. That effort was buttressed by the development of a streamlined infrastructure for conducting Phase I and II clinical trials Meanwhile, the BBRAIN repository provided an infrastructure component which allowed for a more efficient exploration of the mechanisms behind GWI, the identification of biomarkers, etc

443 Polycythemia diminishes, with Hb and Hct levels reverting to sea level norms within a few weeks to months

Extensive, albeit fragmentary, findings from neurochemical and neuroendocrine studies of SZ (Javitt and Laruelle, 2006) have not provided conclusive evidence for any specific etiologic theory of SZ, perhaps due to etiopathogenetic heterogeneity (Tandon et al., 2009)

As shown in Figures 4B, C, L-carnosine treatment significantly reduced IL-6 and TNF- production compared with the model groups, with IL-6 decreased by 2.3-fold in both models and TNF- decreased by 3.3-fold in the LPS model and 1.8-fold in the papain model