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Other approaches to treat large-scale cartilage defects involve shape-filling chondro-inductive biomaterials

Epigenetic events are essential to regulate the condensation state of chromatin and hence to regulate the function of genome by means of histone modifications, chromatin remodeling, DNA methylation and no-coding RNA [9] Fig

TREK-1 receptor is primarily found in the brain region, including the prefrontal cortex and hippocampus, i.e., areas governing mood, memory, and learning