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Double-strand breaks may also occur as repair intermediates during the resolution of oxidatively induced clustered DNA lesions (Sage and Harrison 2011), consisting of closely located lesions, typically within 20 base pairs, which include abasic (AP) sites, oxypyrimidines, oxypurines, and single-strand breaks (Kryston et al

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Results Elevated serine synthesis enzymes are associated with poor prognosis in lung cancer Serine metabolism serves as a central metabolic hub in cancer, primarily fueled glucose and glutamine

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