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how systemic iron disorders (e.g., iron overload or deficiency diseases) modulate cellular ferroptosis susceptibility, and vice versa, has not been systematically addressed

doi: 10.1093/ons/opy283 79 HerkenhamM.LynnA

And there is also a prospective new study (Jagst et al., 2024) that found that hepatitis E tends to convert to chronic infection in immunocompromised patients, and that sofosbuvir is effective in inhibiting hepatitis E virus replication, especially in extrahepatic neuronal cells