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Except for a few genes that are expressed in sperm mitochondria, there is almost no transcription and translation activities ( The most widespread PTM in human sperm studies is phosphorylation, followed by acetylation, and these modifications are essential for sperm differentiation, maturation, and function ( In addition, many studies have proven that obesity can reduce sperm quality and functions, which cause sperm DNA damage, and lead to hypogonadism ( Regulation of Oxidative Stress It has been reported that Kglu is closely related to oxidative metabolism ( The central nervous system has a high metal content, which can catalyze the formation of oxygen free radicals, and its antioxidant defense ability is relatively low, so it is vulnerable to free radical damage ( Regulation of Glutaric Aciduria Type 1 Glutariduria type 1 (GA1), a type of organic aciduria ( Glutaric aciduria 1 is a multi-organ disease, and the organ most affected during metabolic abnormalities in patients is the brain ( Regulation of Chromatin Dynamics Nucleosome is the basic repetitive unit of chromatin

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