Topliss Tree for Aromatic Substitutions There are catalysis geniuses (looking

There are catalysis geniuses (looking at you

take it with you on hikes

• Dimensions: 10

and perfect for your morning java or afternoon tea

Topliss Tree for Aromatic Substitutions There are catalysis geniuses (lookingThe Topliss tree is a simple stepwise process for phenyl group optimization. By making a few compounds sequentially following the Topliss tree, you can quickly identify a more potent tool compound for use in protein co crystallization or a functional assay. The preliminary SAR this generates also helps prioritize your many hits and identify which compounds have no rational SAR and are likely just assay interference compounds. This poster has a partly