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Treatment Iron chelation treatment Despite the novel comprehension of the pathophysiology of -thalassemia, iron chelation therapy still remains the most efficacious approach for reducing the morbidity and mortality associated with iron overload in patients with NTDT and TDT (118)

These interactions contribute to the limited flexibility of the linkage between SRCR2 and SRCR3 in contrast to the flexible linker between SRCR1 and SRCR2 domains, which is twice as long, 10 residues, as shown in Fig

Sikiric et al., 2020a) and thereby, the revealing common resolution (Sikiric et al., 2020a)

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