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Chronobiol Int 2017;34:1003-13

Iron overload was also associated with metabolic remodeling, as evidenced by increased phosphorylation ratios of Akt Thr308 and AMPK (Figure 8H)

We compared islet cell distributions and determined graded intensities of glutathione peroxidase1 (GPX1), a key enzymatic mediator involved in detoxifying hydrogen peroxide, by applying combined immunohistochemistry for GPX1, insulin and glucagon, in pancreatic sections from new-onset T1D (group 1), non-diabetic autoantibody-negative (group 2), non-diabetic autoantibody-positive (group 3) and long-term diabetic (group 4) donors

doi: 10.1007/s12602-022-09998-2 107 MortazEAdcockIMRicciardoloFLVarahramMJamaatiHVelayatiAAet al