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These strategies are useful for a variety of biomedical applications, including drug delivery, imaging, sensing, and theranostics as they can "switch-on" certain functions upon exposure to such intrinsic incitements, such as cargo release from a carrier, enhanced fluorescence output, and higher affinity towards specific biomolecules 4

If peripheral indices parallel central metabolic defects, and perhaps also neuromorphometric and/or neuroimaging findings, then there exists the possibility that alterations in peripheral indices on longitudinal follow-up (repeated measures) can usefully reflect central membrane function over the course of illness

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