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NAC treatment affects excitatory inputs onto MSNs in a cell-type specific manner Next, we asked whether the improvement in behavioral performance induced by NAC treatment was accompanied by changes in the excitability of the accumbal circuitry

The impact of KD on ROS and reactive nitrogen species (RNS) ROS are a group of chemically reactive molecules derived from molecular oxygen that arise primarily as byproducts of mitochondrial oxidative phosphorylation, although they can also be generated by enzymatic systems such as NADPH oxidases, xanthine oxidase, and cytochrome P450 enzymes [63]

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Histopathology of Heart Tissue Hematoxylin & Eosin Staining The heart (left ventricle) tissues fixed in 10% formalin after dissection