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Because the molecule maintains stability in highly acidic or volatile environments, it serves as an excellent benchmark for gastrointestinal tissue research and systemic cell survival studies

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Specifically, at day 7, there is an infiltration of inflammatory cells while controls presented prominent edema, disintegrated reticulin fiber network, and no proliferation of collagen fibers (Figure 9 and Figure 10), and reduction of capillaries with survived arterioles of the myotendinous junction

141,143148 Several lines of evidence have indicated that extracellular loops (EL1 and EL2) of claudins are important for both trans - and cis -claudinclaudin interactions