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In a study conducted by Wang et al

& Webber, D

For instance, recent studies have proposed a CRISPR-Cas9 based tool containing a deactivated Cas9 (dCas9) nuclease fused with a catalytic domain of DNMT and combined with co-expressed sgRNA, which achieves precise DNA methylation for specific targeted regions that are heritable across mitotic divisions in daughter cells [332, 333]