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Denroche HC, Quong WL, Bruin JE et al (2013) Leptin administration enhances islet transplant performance in diabetic mice

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Any fraction that is not conjugated, then undergoes CYP 450 metabolic pathway being converted to cytotoxic metabolite, N-acetyl-p-benzoquinone-imine (NAPQI)

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Injection site reactions including redness and mild swelling are the most common

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