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However, the method for obtaining BMSCs is invasive, the sample size for clinical treatment is relatively limited, and the long-term efficacy is unknown, warranting further research

An analysis of STAR*D showed that treatment with either tranylcypromine or extended-release venlafaxine plus mirtazapine yielded modest remission rates that were not statistically different between the 2 treatment groups.37 Although both treatment groups were similar in quality of response, the lower side effect profile, lack of dietary restrictions, and ease of use of venlafaxine and mirtazapine suggest that the combination may be preferred over the oral MAOI tranylcypromine for patients with treatment-resistant depression

Ubago-Guisado, E

KCC2 function modulates in vitro ictogenesis