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Vitamin B12 deficiency can also cause symptoms that affect your brain and nervous system (neurological symptoms), including: numbness muscle weakness psychological problems, which can range from mild depression or anxiety, to confusion and dementia problems with balance and coordination pins and needles incontinence

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Boers et al, 1985

Moreover, in animals, NNMT knockdown improves insulin sensitivity, overnight fasting glucose levels, and glucose tolerance and reduces the relative fat mass [11, 14]