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demonstrated that when fecal samples from ten healthy individuals were subjected to in vitro colonic fermentation with mixed (poly) phenols, the resulting metabolite profiles were highly personalized, with no consistent correlation in AUC values across subjects

et al., 2022), and when TMAO is combined with PD-1, it has the potential to enhance the antitumor effects of anti-PD-1 (Jia et al., 2023)

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Miczke A, Szuliska M, Hansdorfer-Korzon R, Krgielska-Narona M, Suliburska J, Walkowiak J, Bogdaski P (2016) Effects of Spirulina consumption on body weight, blood pressure, and endothelial function in overweight hypertensive Caucasians : a double-blind, placebo-controlled, randomized trial