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Abstract Previous studies from our laboratory have identified that a carboxy-terminal fragment of the human growth hormone (hGH), hGH(177191), is the lipolytic/anti-lipogenic domain of intact hGH [1]

doi: 10.1054/bjps.2000.3543

The reason could be long-term excessive copper deposition in the liver, which leads to oxidative stress and subsequent oxidative damage to cellular proteins, lipids, DNA, RNA, and mitochondria, resulting in liver cell damage and steatohepatitis

390,391,392 Thus, rosiglitazone has anti-inflammatory effect by decreasing levels of NFB and inhibiting the A42 production in mice, is considering as therapeutic agent for AD