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(PubMed) Dhillon RJ, Hasni S

By integrating shared molecular signatures from plasma EV proteomic and single-cell transcriptomic analyses, we aimed to cross-validate our findings and ensure robust interpretation despite the limitations of the sample size for the sequencing

Furthermore, the mechanisms of their import, including interaction factors and important sequence features, and functions in mitochondria are yet to be elucidated

Conversely, loss of HDAC3 increased ARE activation activity from these sites and diminished cell cycle activity, suggesting that HDAC3 inhibitors may hold promise as a CaP treatment to restore an AR cistrome with more benign features [66]