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3.7 HMC3 as a platform for microglial drug screening As previously mentioned and summarized in Supplementary Table 1 , a broad array of pharmacological agents and genetic manipulation strategies has been applied to HMC3 human microglia, underscoring their value as a robust platform for mechanistic investigation and drug discovery

Adoptive transfer experiments revealed reduced uptake of adoptively transferred GFP + cells into infarcted hearts in the colchicine group ( Supplementary Figure 8D )