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Compared to oral medications like PDE5 inhibitors (e.g., Viagra, Cialis), which require adequate blood flow and sexual arousal to function, injection for erectile dysfunction therapy offers a more predictable and direct response

Aune D, Lau R, Chan D, Vieira R, Greenwood D, Kampman E, Norat T

Nature 530 , 354357 (2016)

This distinction has important implications for therapeutic timing: anti-inflammatory interventions may be most effective if initiated early post-insult to prevent the establishment of chronic tinnitus, but may also confer benefit in established tinnitus by reducing sustained inflammatory signaling that perpetuates maladaptive plasticity