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[34] found strong correlations between symptom severity, especially excessive daytime sleepiness (EDS), cataplexy and sleep disruption with self-care, usual activities, pain and discomfort, anxiety and depression

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SOME INDICATORS OF PEYRONIE'S DISEASE INCLUDE: Plaque formation (felt through the skin as hard lumps) on the penis Painful erections and/or sexual intercourse Erectile dysfunction Shrinkage or narrowing of the penis Symptoms may dissipate without leaving permanent curvature of the penis

Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: oxidative eustress