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Needless to say, there seems to be evidence of both an association of low B12 and early greying, and a reversal of early greying following B12 supplementation

of this final rule with comment period for a summary of comments received on this proposal, as well as the finalized policy and qualifying products for CY 2026

Surgeries like gastric bypass or removing part of the intestine reduce B12 absorption

4,22-24 Due to enterohepatic circulation and kidney reabsorption, humans have extensive stores of B 12 and require several years of inadequate intake to present with a clinical deficiency