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doi: 10.1016/j.jtcvs.2018.02.090 28 WagnerCEPopeNHCharlesEJHuerterMESharmaAKSalmonMDet al

Multiple reproductive abnormalities, including decreased oocyte maturation, disturbed follicular development and ovulation, heightened rates of follicular atresia, and eventually infertility, are caused by conditional deletion of Dicer1 exclusively in mammalian follicular granulosa cells (GCs) [87,88,89]