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ABHD5 was first described as the causative gene in Chanarin-Dorfman syndrome (CDS), a disease marked by neutral lipid storage and ichthyosis (32, 33)

J Clin Endocrinol Metab 76 : 309317 Kim KR et al

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In some cases, especially at the beginning of treatment for a severe deficiency, injections might be given more frequently (e.g., daily or every other day) for a short period before transitioning to a maintenance schedule