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Breast cancer cells have also been shown to inhibit apoptosis via phosphorylation of the p44/42 MAPK and Akt/protein kinase B signaling through the TF-FVIIa-FXa complex (rather than thrombin), activating the mammalian target of rapamycin (mTOR) pathway, which results in cell migrationan important step in metastasis [103]

4.16 Statistics All normalized values were transferred to GraphPad Prism 8.4.3 for statistical analysis of biological replicates

The DDSP models have the fewest parameters (up to 10 times less), despite no effort to minimize the model size in these experiments

This conservative approach provides maximum receptor recovery and works well for long-term users planning multiple cycles over a year or more