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The left-right rotational asymmetry of this twist is determined by the LIN-12/Notch pathway and involves LAG-2, APX-1 and LAG-1 proteins

10.1038/nrn894 26 De AndradeD

This study proved the findings of others that therapy with HU in SCA patients, reduces pain episodes, blood transfusions, and in hospital days.[ , , ] Moreover, the study reported that combining LC with HU enhances all these effects

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