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Such disruptions in energy metabolism facilitate the accumulation of brain amyloid-beta (A) and aggregation of tau, leading to oxidative stress, inflammation, impaired autophagy, and various disease-causing cascades

[DOI] [PMC free article] [PubMed] [Google Scholar] [74].Modrick ML, Didion SP, Lynch CM, Dayal S, Lentz SR, Faraci FM, Role of hydrogen peroxide and the impact of glutathione peroxidase-1 in regulation of cerebral vascular tone

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Clinical Background (Summary and Explanation of the Test) Glucose-6-phosphate dehydrogenase (G-6-PD) is a cytoplasmic enzyme that is distributed in all cells