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Signaling through the phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) axis is responsible for aerobic glycolysis mediated by glucose transporter in epidermal growth factor receptor (EGFR)-mutated lung adenocarcinoma

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To create molecularly focused therapies that can change the course of the illness rather than merely manage its symptoms, it is necessary to map the sequential path from airway to damage to systemic and neurological harm [107, 108]