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Similarly, fucoidan promotes cytotoxic T-lymphocytes proliferation and cytokine production, significantly suppressing CT-26 carcinoma growth in vivo (Zhou et al., 2024)

2.2.3 Activation of the MAPK signaling pathway MAPK are pivotal signaling mediators that respond to diverse stimuli, including physiological signals (e.g., hormones, cytokines, and growth factors) and stress-related cues (e.g., endogenous stress and environmental perturbations)