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J Physiol Pharmacol (2006) 57:32942

Thousands of compounds, including approved drugs and molecules in clinical trials, have been screened against this target, but the hit rate is extremely low compared with that of drug leads that target M pro , another viral protease encoded by SARS-CoV-2

On the other hand, certain chemical compounds called peptides show promise in boosting the bodys natural ability to heal itself

Evidence is accumulating to demonstrate that inhibitors of H 2 S production or therapeutic H 2 S donor compounds exert significant effects in various animal models of inflammation, reperfusion injury and circulatory shock