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Toxicology 278, 211216

Cellular mechanisms that exist to counteract ROS include stabilization by enzymes such as superoxide dismutase and catalase, and direct scavenging by antioxidant molecules such as glutathione (GSH), a major intracellular antioxidant

The harvest protein was stored at 80 C for subsequent analysis

Hyperglycemia causes pericyte damage, endothelial cell dysfunction, and basement membrane thickening in retinal vessels, leading to disruption of the blood-retinal barrier (108)