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They were found to contain carnitine acetyltransferase (CRAT), firmly bound to the inner face of the inner mitochondrial membrane and four CPT isoenzymes, named CPT-IA in liver, CPT-IB muscle and most other cells, CPT-IC in brain and testis [7] and CPT-II

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These transporters all adopt the major facilitator superfamily (MFS) fold and are capable of translocating a range of different molecules across the plasma membrane, including endogenous substrates, clinically relevant drugs and xenobiotics 12