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Description

Genomics 52 , 2438 (2025)

AMPK activation inhibits the functions of myeloid-derived suppressor cells (MDSC): impact on cancer and aging

in biological terms it performs a cell protective activity in biological tissues through its antioxidant action and as a combination agent for metabolites to be disposed of by the organism

The analysis of data for both time points revealed significant upregulation of genes in various pathways, especially those related to general metabolism, GSH metabolism, and oxidative stress, such as oxidative phosphorylation and ROS, in hepsin / mice compared with wild-type mice (Fig