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This includes upregulation of antioxidant enzymes (superoxide dismutase, catalase) that protect against oxidative damage, enhancement of growth factor expression (TGF-, VEGF, PDGF) that supports tissue repair, and suppression of inflammatory gene expression that contributes to chronic skin degradation

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It has been used in therapeutic settings for sleep disorders and stress-related conditions with minimal reported complications, making it a safe option when integrated into a personalized health plan

[DOI] [PubMed] [Google Scholar] 46.Zhai H., Poblete N., Maibach H