glutathione s transferase ncbi

glutathione s transferase ncbi The role of glutathione-S-transferase in anti-cancer drug resistance Glutathione transferases as mediators of

Name: glutathione s transferase ncbi The role of glutathione-S-transferase in anti-cancer drug resistance Glutathione transferases as mediators of
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Glutathione transferases as mediators of signaling pathways involved in cell proliferation and cell death Cell Death & Differentiation Glutathione S Transferases in Cancer PMC Glutathione S transferase Wikipedia The role of glutathione S transferase in anti cancer drug resistance Oncogene

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Description

A small-molecule inhibitor suppresses the tumor-associated mitochondrial NAD(P)+-dependent malic enzyme (ME2) and induces cellular senescence

Specifically, P1-derived fibroblasts, which contain 350 GAA repeats in each allele, exhibited a 60% reduction in gene expression, while P2-derived fibroblasts, with 450 and 560 GAA repeats in each allele, showed an 80% reduction in comparison to control fibroblasts