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Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy

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It was first suggested that importation of StAR into mitochondria formed contact points between the OMM and IMM, permitting cholesterol to flow down a chemical concentration gradient (136, 199), and others concluded that the 30 kDa mature StAR is the biologically active moiety, functioning as a cholesterol shuttle in the intramembranous space (207)

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Prin combinarea celorlalte ingrediente, vedem un beneficiu sinergic (combinat) care pare sa sustina functii precum productia de energie celulara, cresterea capacitatii antioxidante, conservarea membranei celulare, compensarea stresului oxidativ, reducerea inflamatiei si chiar cresterea nivelului de oxid nitric