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Graphical abstract Access this article Data availability The data were statistically analyzed and shown in figures and tables

Limitations There are some limitations to this review that warrant discussion

10.1111/j.1469-8137.2005.01487.x New Phytol

These tests may include 25 : Complete blood count (CBC) to screen for anemia and conditions affecting red or white blood cells or platelets Comprehensive metabolic panel to check kidney function and general health status Erythrocyte sedimentation rate (ESR) and/or C-reactive protein (CRP) to screen for inflammatory disorders Thyroid stimulating hormone (TSH) to rule out thyroid disease 25-hydroxy vitamin D to identify cases of deficiency Ferritin to assess iron status, especially in those with fatigue, cognitive dysfunction, restless leg syndrome, or a high risk of deficiency Vitamin B12 to test for deficiency, especially in cases involving cognitive dysfunction Various additional blood tests may be ordered when indicated to rule out other suspected diagnoses, such as autoimmune diseases, muscle diseases, neurologic disorders, and infections