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2 There is also a much-discussed link to the Wnt/-catenin pathway, which is a genuine master regulator of the hair cycle: active -catenin signaling in the dermal papilla drives follicles into anagen and enhances their hair-inducing capacity, while reduced signaling is associated with regression and miniaturization

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In May 2023, a prospective, multi-center, randomized controlled clinical trial was conducted to assess the efficacy of the Qingyi Huaji Optimized Formula, a TCM formulation comprising seven medicinal constituents including Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, Rhizoma Arisaematis, Fructus Amomi Rotundus, Ganoderma, Herba Gynostemmatis, and Semen Coicis, in patients who were diagnosed with stage IV pancreatic ductal adenocarcinoma and were undergoing gemcitabine treatment (NCT05840341)

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