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These comprise long and small ncRNAs, which are crucial for regulating gene expression, chromatin remodeling, RNA splicing, and other vital cellular regulatory processes but do not produce proteins [534]

tesamorelin if visceral fat is the primary target Starting dose 50% of standard adult dose, titrated up over 46 weeks based on IGF-1 response and side effect tolerance Administration subcutaneous injection, typically at bedtime to align with natural GH pulsatility 8-week reassessment IGF-1, fasting glucose, HbA1c, symptom review, body composition measurement Ongoing monitoring every 812 weeks

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