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Clinical research has demonstrated that AOD-9604 can produce meaningful metabolic effects and body composition improvements, particularly in reducing abdominal and visceral fat deposits

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Two antisense oligonucleotides that specifically interact with the mRNAs of the protein kinase C-, responsible for tyrosinase phosphorylation and thus its activation [115], decreased tyrosinase activity in cultured melanocytes and reduced hand pigmentation in volunteers after applying a care product containing these synthetic agents [116]