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Specifically, UV irradiation can mediate damage of lens structures, due to: direct absorption of the incident light by the cellular components, resulting in excited state formation and subsequent chemical reaction, and photosensitization mechanisms, where the light is absorbed by endogenous photosensitizers that are excited to their triplet states 6

MiR-139 acted as a radiosensitizer by inhibiting NRF2 signaling, enhancing IR-induced peroxidation of lipid and ferroptosis in NSCLC cells

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3.1.3 Glutathione Glutathione (GSH), serving as the main antioxidant inside cells, is vital in maintaining oxidative balance within cells