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The samples were desalted using a Zeba spin desalting column (Thermo Fisher Scientific) and 100 l of the desalted sample was combined with 100 l of 100 M NADPH

The current hypothesis suggests that upon recruiting BMSCs, E7 first activates the binding of SDF-1 to the C-X-C chemokine receptor type 4 (CXCR4) receptor before regulating the proliferation, differentiation, and migration of BMSCs through the p38(MAPK), Ras-Erk1/2, and the PI3K-Akt signaling pathways [72]

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