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10.1038/srep26933 143 TripathiB

Losing 2 to 3 pounds per week or more increases the proportion of lean mass lost alongside fat

Specifically, eligible studies included participants (P) with a confirmed diagnosis of vitamin B12 deficiency, interventions (I) involving oral or sublingual vitamin B12 administration, comparators (C) using intramuscular supplementation, and outcomes (O) reporting changes in serum vitamin B12 or homocysteine levels