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Both male hemizygotes and female homozygotes with G6PD gene deficiency manifest show significantly reduced G6PD enzyme activity, while 80% of female heterozygotes show moderately reduced G6PD enzyme activity

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Extra-gastrointestinal IBD symptoms (outside the gut) include eye inflammation, joint pain, and extreme fatigue

And one could ask: Is it even ethical if you dont think patients will benefit from opioids? Rather than placing fibromyalgia patients on opioids, Martucci is evaluating patients who are already being prescribed these medications