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This unique mechanism makes it a powerful research compound for investigating melanogenesis, skin pigmentation pathways, and peptide signaling

Common side effects may include : Nausea (especially at higher doses) Facial flushing or warmth Headache Injection site irritation Transient increase in blood pressure These effects are usually mild and resolve within hours

Histologically, amelanotic melanomas require the use of special stains because of the pathologic mimics

Don't wait if you experience any of the following: Signs of Infection: Fever (temperature over 100.4F or 38C) Increased redness, warmth, or swelling around the incision that is spreading Pus or thick, foul-smelling discharge from the wound Increasing pain that is not relieved by pain medication Excessive Bleeding: If your dressing becomes quickly soaked with blood, or if bleeding doesn't stop after applying firm pressure for 15-20 minutes