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The commonly explored processes include but are not limited to a transport process mediated by the transferrin receptor (TfR), insulin receptor, members of the LDL receptor family for receptors-mediated processes [8] and by the glucose transporter (GLUTs) and amino acid transporter for carrier (transporter)-mediated processes [18]

However, oxidative/nitrosative stress and inflammatory conditions, which are typical for neurodegenerative disorders such as Alzheimer's disease, may disturb this fragile balance between metals and consequently disrupt zinc homeostasis, resulting in the uncontrolled release of zinc and amyloid deposition

doi:10.1016/j.seizure.2010.10.027 6

The results of Look AHEAD do not row against the implementation of lifestyle changes in patients with type 2 diabetes