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Vunta H, Belda BJ, Arner RJ et al (2008) Selenium attenuates pro-inflammatory gene expression in macrophages

Shockingly, one-third of OTC ELGSs contain potent PGAs such as isopropyl cloprostenate (ICP)

Oxidative stress and signaling through EGFR and PKA pathways converge on the nuclear transport factor RanBP1

in vitro screening study of recombinant DIOs found that 411 (22.5%) of the 1851 compounds from the ToxCast Phase 2 and e1k libraries inhibited DIO1, DIO2 and/or DIO3 by more than 20%, and that 228 (12.5%) inhibited a DIO by at least 50% [112]